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📝 JAMA Patient Page: Postural orthostatic tachycardia syndrome (#POTS) is a chronic disorder that causes an abnormal increase in heart rate with standing and is associated with symptoms such as lightheadedness, palpitations, fatigue, exercise intolerance, gastrointestinal symptoms, and cognitive problems. Diagnosis is based on characteristic symptoms and a sustained rise in heart rate during standing without a significant decline in blood pressure. https://ja.ma/4zfQufL

Today is #WorldDiabetesDay Can you spot the symptoms of diabetes? •Feeling very thirsty •Peeing frequently •Experiencing blurry vision •Feeling tired •Wounds healing slowly •Having frequent infections Type 1 diabetes often develops rapidly. Seek medical advice immediately if you spot diabetes symptoms. Type 2 diabetes typically develops gradually and may cause few or no noticeable symptoms. If you think you may have #diabetes, speak to a doctor or health worker https://bit.ly/2026WorldDiabetesDay ✏️ Visual by @miss__diabetes

By your 70s, even vigorous exercise may do little to reverse a stiffened heart. In a small study from (previous FMF guest) Dr. Ben Levine’s team, sedentary adults around age 70 trained for a year. Their VO2 max rose 19%, but heart stiffness changed little. Midlife appears to offer a better window. When sedentary adults ages 45–64 completed two years of structured training that included vigorous intervals, their VO2 max rose 18%, and heart stiffness improved. The heart can still respond to training later in life. But changing its stiffness may require sustained, demanding exercise before those changes become harder to reverse.

A study in mice finds that mechanical strain on the skeleton—the pushing, pulling, and twisting that normally happen during exercise and other forms of physical activity—triggers force-sensing bone cells called osteocytes to secrete antiaging chemicals. The research team found they could extend mouse lives by nearly 3 months—the equivalent of about nine human years—just by gently squeezing their leg bones. https://scim.ag/4BFJCKY

As our brain ages, there is disruption of the flow of cerebrospinal fluid during sleep @NatureAging https://www.nature.com/articles/s43587-026-01270-4

Original Article: Rivaroxaban Then Aspirin vs. Aspirin Alone after Total Hip or Knee Arthroplasty (EPCAT III trial) https://nej.md/44j0Bne Editorial: Aspirin Therapy — Enough after Arthroplasty https://nej.md/3UoXzwn #Surgery #Orthopedics

Stop scrolling and learn the 4 Ts for World Diabetes Day! Type 1 diabetes can happen at any age and if left undiagnosed, it can be fatal. The most common symptoms are the 4 Ts: Toilet, Thirsty, Tired, Thinner. ℹ️ https://www.nhs.uk/conditions/type-1-diabetes/symptoms/

#Diabetes has different types, and all affect blood glucose. But the role of insulin differs in each. So this #WorldDiabetesDay, explore with us to understand the differences & speak to a healthcare professional about any concerns. #ActEarlyOnDiabetes